Poster Information

  1. Development and Characterization of Novel PVA/Starch/g-C3N4 Titanium Doped Silver Nanoparticles Hydrogel Membrane for Wound Dressing.

    Arooj Ahmed and Muhammed Bilal Khan Niazi

    School of Chemical and Materials Engineering (SCME), National University of Sciences & Technology (NUST) H-12, Islamabad, Pakistan
  2. Efficient Synthetic Biological Modification of Human Mesenchymal Stem Cells.

    Richard Balint and Eriko Takano

    Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom
  3. Engineering Protein-Protein Devices for Multilayered Regulation of mRNA Translation Using Orthogonal Proteases in Mammalian Cells.

    Federica Cella1, Liliana Wroblewska2, Ron Weiss3, and Velia Siciliano4

    (1)University of Genoa, Genoa, Italy, (2)Pfizer Inc, Cambridge, MA, (3)Biological Engineering, M.I.T., Cambridge, MA, (4)NBT Department, Italian Institute of Technology, Genoa, Italy
  4. Building a Better Cell-Based Assay Reporter Assay By Tuning Expression.

    Melissa Chiasson1, Kenneth Matreyek1, Allan Rettie2, and Douglas Fowler1

    (1)Genome Sciences, University of Washington, Seattle, WA, (2)Medicinal Chemistry, University of Washington, Seattle, WA
  5. Stimulating Dissociation of Cas9 from Double-Strand DNA Breaks.

    Ryan Clarke

    Biochemistry and Molecular Genetics, UNIVERSITY OF ILLINOIS AT CHICAGO, CHICAGO, IL
  6. Software for Automating the Design of Mammalian Genetic Programs.

    Christopher T. Coleman1,2, Joseph J. Muldoon2,3, Jonathan D. Boucher2,3, Patrick S. Donahue2,3,4, and Joshua N. Leonard2,3,5,6,7

    (1)Computer Science, Northwestern University, Evanston, IL, (2)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (3)Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, (4)Medical Scientist Training Program, Feinberg School of Medicine, Chicago, IL, (5)Member, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (6)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, (7)Center for Synthetic Biology, Northwestern University, Evanston, IL
  7. Withdrawn
  8. Modeling the Efficacy and Potency of In Vivo Somatic Cell Gene Correction for Pompe Disease.

    Jared Carlson-Stevermer1, Amritava Das1, David Fiflis1, Amr A Abdeen1, Heidi Kletzein2, Madelyn Goedland1, Lucille Kohlenberg1, and Krishanu Saha1

    (1)Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, (2)Surgery, University of Wisconsin - Madison, Madison, WI
  9. Design-Driven Engineering of Split Protein-Based Biosensors for Extracellular Cues.

    Taylor Dolberg1, Anthony Merger2, Srivatsan Raman2, and Joshua N. Leonard1

    (1)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (2)Biochemistry, University of Wisconsin-Madison, Madison, WI
  10. A Hypoxia Biosensor for Anti-Tumor Therapy and Longitudinal Imaging of Disease Progression.

    Patrick S. Donahue1,2,3, Katherine J. Zhu4, Hailey I. Edelstein1, Benji D. Leibowitz1, and Joshua N. Leonard1,5,6,7

    (1)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (2)Medical Scientist Training Program, Feinberg School of Medicine, Chicago, IL, (3)Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, (4)Georgia Institute of Technology, Atlanta, GA, (5)Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (6)Center for Synthetic Biology, Northwestern University, Evanston, IL, (7)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL
  11. Orthogonal Chemically-Inducible Regulators of Mammalian Gene Expression.

    Joseph W. Draut1, Brandon L. Lim1, Patrick S. Donahue1,2,3, Katelyn Dray1, and Joshua N. Leonard1,3,4,5,6

    (1)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (2)Medical Scientist Training Program, Feinberg School of Medicine, Chicago, IL, (3)Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, (4)Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (5)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, (6)Center for Synthetic Biology, Northwestern University, Evanston, IL
  12. Rapid, Quantitative Characterization of Mammalian Synthetic Biology Devices Using the Chemically Inducible Prototyping System (ChIPS).

    Kate Dray1, Patrick S. Donahue1,2,3, Joseph W. Draut1, Brandon Lim1, Joseph J. Muldoon1,3, Neda Bagheri1,3,4,5,6,7,8, and Joshua N. Leonard1,3,4,5,9

    (1)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (2)Medical Scientist Training Program, Feinberg School of Medicine, Chicago, IL, (3)Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, (4)Center for Synthetic Biology, Northwestern University, Evanston, IL, (5)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, (6)Northwestern Institute on Complex Systems, Northwestern University, Evanston, IL, (7)Member, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (8)NSF-Simons Center for Quantitative Biology, Northwestern University, Evanston, IL, (9)Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL
  13. Programmable Protein Circuits in Living Cells.

    Xiaojing Gao1, Lucy Chong1, Matthew Kim1, and Michael Elowitz2

    (1)Caltech, Pasadena, CA, (2)California Institute of Technology, Pasadena, CA
  14. Prototyping Protein-Protein Interaction-Based Logic Using Cell-Free Protein Synthesis.

    Andrew Hunt1, Zibo Chen2, David Baker2, and Michael C. Jewett3

    (1)Chemical Engineering, New Mexico Institute of Mining and Technology, Albuquerque, NM, (2)Department of Biochemistry, University of Washington, Seattle, WA, (3)Chemical and Biological Engineering, Northwestern University, Evanston, IL
  15. Directed Evolution of Bacteria-Derived Gas Nanostructures As Acoustic Reporter Genes.

    Robert C. Hurt1, Daniel P. Sawyer2, David Mittelstein3, and Mikhail G. Shapiro4

    (1)Division of Biology and Biological Engineering, Caltech, Pasadena, CA, (2)Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, (3)Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, (4)Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA
  16. Anti-CRISPR Mediated Regulation of CRISPR/Cas9 Based Genome Engineering in Mammalian Cells.

    Surbhi Jain1, Shireen Abesteh2, Sherri Ho3, Ipek Tasan4, Teresa Martin5, and Huimin Zhao6

    (1)Department of Biochemistry, University of Illinois at Urbana Champaign, Urbana, IL, (2)Molecular and Cellular Biology, University of Illinois Urbana Champaign, Urbana, IL, (3)University of Illinois at Urbana-Champaign, Urbana, IL, (4)Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, (5)CHEMICAL AND BIOMOLECULAR ENGINEERING, University of Illinois Urbana Champaign, Urbana, IL, (6)Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL
  17. Accurate Control of Gene Expression in Mammalian Cells Using a CRISPR Endoribonuclease-Based Incoherent Feedforward Loop.

    Ross Jones1, Yili Qian2, Breanna DiAndreth1, Velia Siciliano3, Domitilla Del Vecchio2, and Ron Weiss4

    (1)Biological Engineering, MIT, Cambridge, MA, (2)Mechanical Engineering, MIT, Cambridge, MA, (3)NBT Department, Italian Institute of Technology, Genoa, Italy, (4)Biological Engineering, M.I.T., Cambridge, MA
  18. Development of a Split Esterase for Detecting Molecular Interactions in Live Cells.

    Krysten Jones1, Kaitlin Kentala1, Weiwei An2, Alexander Lippert2, Jared Lewis3, and Bryan Dickinson1

    (1)Chemistry, University of Chicago, Chicago, IL, (2)Chemistry, Southern Methodist University, Dallas, TX, (3)Chemistry, Indiana University Bloomington, Bloomington, IN
  19. Bxb1-GA for Highly Efficient Site-Specific Payload Integration in Mammalian Cells.

    Barbara Jusiak1, Ron Weiss2, and Timothy Lu3

    (1)Research Laboratory of Electronics, MIT, Cambridge, MA, (2)Biological Engineering, M.I.T., Cambridge, MA, (3)MIT, Cambridge, MA
  20. Engineering Multi-Input Mammalian Biosensors Using Transcriptional and Enzymatic Cascades.

    Viswajit Kandula1,2, Joseph J. Muldoon1,3, Mihe Hong1, and Joshua N. Leonard1,3,4,5,6

    (1)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (2)Biomedical Engineering, Northwestern University, Evanston, IL, (3)Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, (4)Member, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (5)Center for Synthetic Biology, Northwestern University, Evanston, IL, (6)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL
  21. High-Pass Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation.

    Taek Kang1, Tyler Quarton1, Kristina Ehrhardt1, Chance M. Nowak2, Abhyudai Singh3, Yi Li1, and Leonidas Bleris1

    (1)Bioengineering, The University of Texas at Dallas, Richardson, TX, (2)Biological Sciences, The University of Texas at Dallas, Richardson, TX, (3)Electrical & Computer Engineering, University of Delaware, Newark, DE
  22. Elucidating the Effect of Transmembrane Domain Choice on Synthetic Receptor Signaling and Structure.

    Anthony K. Kang1, Hailey I. Edelstein2, Patrick S. Donahue2,3,4, Lauren Battaglia2, Everett R. Allchin2, and Joshua N. Leonard2,5,6,7

    (1)Program in Biological Sciences, Northwestern University, Evanston, IL, (2)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (3)Medical Scientist Training Program, Feinberg School of Medicine, Chicago, IL, (4)Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, (5)Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (6)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, (7)Center for Synthetic Biology, Northwestern University, Evanston, IL
  23. Toward a Translationally-Independent Guide RNA Oscillator.

    James Kuo1,2, Ruoshi Yuan1, Johan Paulsson1, and Pamela A. Silver1

    (1)Systems Biology, Harvard Medical School, Boston, MA, (2)Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA
  24. Withdrawn
  1. Programming and Reprogramming Neural Cell Types Using Synthetic Transcription Factors.

    Mantas Matjusaitis

    Centre of Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom
  2. Improved Methods for Recombinase-Mediated Multiplex Assessments of Variant Libraries in Mammalian Cells.

    Kenneth Matreyek, Jason Stephany, Melissa Chiasson, and Douglas Fowler

    Genome Sciences, University of Washington, Seattle, WA
  3. Biogenic Metallic Nanoparticles. from Microbiological Biofactories to Nanometric Trojan Horses..

    David Medina, Junjiang Chen, and Thomas J. Webster

    Chemical Engineering, Northeastern University, Boston, MA
  4. Design-Driven Engineering of Logic-Gated Receptor Signaling Cascades in Mammalian Cells.

    Joseph J. Muldoon1,2, Viswajit Kandula1,3, Mihe Hong1, Patrick S. Donahue1,2,4, Neda Bagheri1,2,5,6,7,8,9, and Joshua N. Leonard1,2,6,7,8

    (1)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (2)Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, (3)Biomedical Engineering, Northwestern University, Evanston, IL, (4)Medical Scientist Training Program, Feinberg School of Medicine, Chicago, IL, (5)NSF-Simons Center for Quantitative Biology, Northwestern University, Evanston, IL, (6)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, (7)Member, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (8)Center for Synthetic Biology, Northwestern University, Evanston, IL, (9)Northwestern Institute on Complex Systems, Northwestern University, Evanston, IL
  5. An Artificial Mechanogenetic Circuit for Targeted Gene Activation.

    Robert J. Nims1,2, Lara Pferdehirt1,2,3, Alison K. Ross1,2,3, Jeremiah Lorentz1,2,3, Alireza Savadipour1,2,4, and Farshid Guilak1,2,3,4

    (1)Orthopaedic Surgery, Washington University in St. Louis, St. Louis, MO, (2)Shriners Hospitals for Children - St. Louis, St. Louis, MO, (3)Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, (4)Mechanical Engineering, Washington University in St. Louis, St. Louis, MO
  6. Tracing Cell Lineages Using Annotating DNA Elements.

    Hannah M. Pennington and Bradley J. Merrill

    Biochemistry and Molecular Genetics, University of Illinois, CHICAGO, IL
  7. Thermal Bioswitches for Modular Control of Protein Dimerization.

    Dan Piraner1, Yan Wu2, and Mikhail G. Shapiro2

    (1)Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, (2)Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA
  8. A Flight Simulator for Cancer Immunotherapy: Modeling CAR T-Cells in a Solid Tumor Context.

    Alexis Prybutok1, Joshua N. Leonard1,2,3,4, and Neda Bagheri1,2,3,4,5,6

    (1)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (2)Member, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (3)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, (4)Center for Synthetic Biology, Northwestern University, Evanston, IL, (5)Northwestern Institute on Complex Systems, Northwestern University, Evanston, IL, (6)NSF-Simons Center for Quantitative Biology, Northwestern University, Evanston, IL
  9. Metabolic Properties of Mouse Spermatogenesis Defined through Constraint-Based Modeling.

    Kourosh Salehi-Ashtiani1, Bushra Dohai2, Amphun Chaiboonchoe2, and Erwin Goldberg3

    (1)Center for Genomics and Systems Biology (CGSB), New York University Abu Dhabi, Abu Dhabi, United Arab Emirates, (2)Division of Science and Math, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates, (3)Molecular Biosciences, Northwestern University, Evanston, IL 60208, IL
  10. Elucidating Design Rules for Integrating Mammalian Genetic Programs into the Genome.

    Parth V. Shah1,2, Hailey I. Edelstein2, Joseph J. Muldoon2,3, Patrick S. Donahue2,3,4, Siyuan Feng5, and Joshua N. Leonard2,6,7,8

    (1)Biological Sciences, Northwestern University, Evanston, IL, (2)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (3)Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, (4)Medical Scientist Training Program, Feinberg School of Medicine, Chicago, IL, (5)Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, (6)Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, (7)Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, (8)Center for Synthetic Biology, Northwestern University, Evanston, IL
  11. Cell-Free Technologies for Customizable Glycoprotein Therapeutic and Vaccine Production.

    Jessica C. Stark1, Thapakorn Jaroentomeechai2, Jasmine M. Hershewe1, Rachel Dubner3, Karen Hsu4, Matthew P. DeLisa2, and Michael C. Jewett1

    (1)Chemical and Biological Engineering, Northwestern University, Evanston, IL, (2)Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY, (3)Biological Sciences, Northwestern University, Evanston, IL, (4)Mechanical Engineering, Northwestern University, Evanston, IL
  12. Reversible Gene Regulation in Mammalian Cells Using Riboswitch-Engineered Vesicular Stomatitis Virus Vector.

    Kei Takahashi1 and Yohei Yokobayashi2

    (1)Nucleic Acid Chemistry and Engineering Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa, Japan, (2)Nucleic Acid Chemistry and Engineering Unit, Okinawa Institute of Science and Technology, Okinawa, Japan
  13. Two-Color Imaging of Non-Repetitive Endogenous Loci in Human Cells By Knock-in of Orthogonal Repeat Arrays.

    Ipek Tasan1, Christina Su2, Behnam Enghiad3, Shekhar Mishra3, and Huimin Zhao3

    (1)Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, (2)Department of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL, (3)Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL
  14. A Novel Cas9 Mutant Confers Reduced Off-Target Gene Editing While Maintaining on-Target Potency.

    Rolf Turk1, Christopher Vakulskas1, Daniel Dever2, Garrett Rettig1, Michael Collingwood1, Ashley Jacobi1, Ciaran Lee3, Joab Camarena2, Matthew H. Porteus2, Gang Bao3, and Mark Behlke1

    (1)Integrated DNA Technologies, Coralville, IA, (2)Department of Pediatrics, Stanford University, Stanford, CA, (3)Department of Bioengineering, Rice University, Houston, TX