Image courtesy of Cell Signaling Technology (cellsignal.com)

Saturday May 11, 2013

8:45amWelcome, objectives, process

Ron Weiss, MIT

9:00amMammalian synthetic biology tools
  • Martin Fussenegger, ETH: "Prosthetic networks: A new treatment strategy for metabolic disorders"
  • Pam Silver, Harvard: "Designing systems to interrogate and re-program cell state"
  • Philip Gregory, Sangamo BioSciences: "Genome editing with zinc finger nucleases"
11:00amMammalian synthetic biology tools
  • Ron Weiss, MIT: "From parts to modules to therapeutic systems using mammalian synthetic biology"
  • Philip Dormitzer, Novartis: "Synthetic vaccines: Synthetic biology approaches the clinic"
1:00pmTechnology-focused breakout sessions
  • Advances in DNA assembly and delivery
  • Advances in transcriptional regulation
  • Advances in sensors and actuators
  • Advances in non-transcriptional regulation
  • Doug Melton, Harvard: "Multiple routes to investigate type 1 diabetes"
  • David Schaffer, Berkeley: “Molecular engineering and evolution of new viruses for mammalian gene delivery”
  • Harvey Lodish, MIT: "Genetically and chemically modified red blood cells as novel therapeutics, immunomodulatory agents, and imaging probes"
  • Tyler Jacks, MIT: "Modeling cancer in the mouse"
4:30pmDisease and scientific inquiry focused-breakout sessions
  • Opportunities and challenges in cancer
  • Opportunities and challenges in stem cells and tissue engineering
  • Opportunities and challenges in vaccination and infectious disease
  • Opportunities and challenges in diabetes and metabolic diseases
  • Opportunities and challenges in neurosciences
  • Opportunities and challenges in scientific inquiry
  • Opportunities and challenges in drug screening
6:00pmPoster session and buffet dinner
8:00pmEnd of day's activities

Sunday May 12, 2013

8:45am Foundations & Applications
  • James Collins, Boston University: "Mammalian synthetic biology and biomedical applications"
  • Christina Smolke, Stanford: "RNA-based control systems for regulating cell fate in human cells"
  • Linda Griffith, MIT: "Human physiome on a chip + synthetic biology = Better drugs, faster and cheaper"
10:30amReports from breakout sessions